Open science is a key principle of the Innovative Training Network (ITN) ChromDesign, which aims to advance our understanding of chromatin biology and epigenetic regulation. As part of this commitment to openness and transparency, the ChromDesign network has produced a collection of high-quality datasets that are freely available to the scientific community. These datasets represent a valuable resource for researchers working in the field of chromatin biology and are a reflection of the network’s dedication to promoting collaboration, sharing knowledge, and advancing scientific discovery. The collection of datasets will be continually updated to ensure that the latest research findings are made available to the scientific community, further promoting open science principles.